Search on: TREATMENT-RELATED CANCER 
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Descriptor English:   Neoplasms, Second Primary 
Descriptor Spanish:   Neoplasias Primarias Secundarias 
Descriptor Portuguese:   Segunda Neoplasia Primária 
Synonyms English:   Neoplasms, Therapy-Related
Neoplasms, Treatment-Related
Second Malignancy
Second Neoplasm
Second Primary Neoplasms
Neoplasms, Metachronous
Neoplasms, Metachronous Second Primary
Therapy-Associated Neoplasms
Therapy-Related Cancer
Treatment-Associated Neoplasms
Treatment-Related Cancer  
Tree Number:   C04.692
Definition English:   Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause. 
Indexing Annotation English:   a 2d or more neopl of same or different histol type at same or different sites: do not confuse with NEOPLASMS, MULTIPLE PRIMARY (see note there); often follows ther (note X refs); IM; coord with each specific histol type (IM) & each precoord organ/neopl term (IM); do not use /compl with specific multiple neopl terms to show multiplicity; Manual 24.4.1.7; differentiate from NEOPLASM METASTASIS (Manual 24.4.1.3+) & NEOPLASM RECURRENCE, LOCAL: Manual 24.4.1.5
See Related English:   Neoplasms, Multiple Primary
 
History Note English:   92 
Allowable Qualifiers English:  
BS blood supply BL blood
CF cerebrospinal fluid CI chemically induced
CH chemistry CL classification
CO complications CN congenital
DI diagnosis DH diet therapy
DT drug therapy EC economics
EM embryology EN enzymology
EP epidemiology EH ethnology
ET etiology GE genetics
HI history IM immunology
ME metabolism MI microbiology
MO mortality NU nursing
PS parasitology PA pathology
PP physiopathology PC prevention & control
PX psychology RA radiography
RI radionuclide imaging RT radiotherapy
RH rehabilitation SC secondary
SE secretion SU surgery
TH therapy US ultrasonography
UL ultrastructure UR urine
VE veterinary VI virology
Record Number:   29936 
Unique Identifier:   D016609 

Occurrence in VHL:
 

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